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Stoner Dale Denton's (Seth Rogen) enjoyment of a rare strain of marijuana may prove fatal when he drops his roach in a panic after witnessing a murder. Upon learning that the fancy weed can be traced back to them, Dale and his dealer (James Franco) go on the lam, with a dangerous drug lord (Gary Cole) and crooked cop (Rosie Perez) hot on their heels.

Starring
Seth Rogen Dale Denton
James Franco Saul Silver
Gary Cole Ted Jones
Rosie Perez Carol/Female Cop
Danny McBride Red
Kevin Corrigan Budlofsky
Craig Robinson Matheson
Amber Heard Angie Anderson
Ed Begley Jr. Robert
Nora Dunn Shannon
Bobby Lee Bobby
James Remar Gen. Bratt

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